How Long After Stopping Progesterone Will I Miscarry? [Answered]

How long after stopping progesterone will I miscarry? Some women who experience miscarriages turn to progesterone to help them.

According to research, doing progesterone treatment might save 8,450 miscarriages per year.

The data has been perplexingly mixed. It indicates that the underlying narrative of progesterone is more complicated. Let’s find out the complete story in the article below.

What Is Progesterone?

how long after stopping progesterone will i miscarry

Progesterone is a natural hormone primarily generated by the adrenal glands and ovaries. It is also created by the placenta during pregnancy.

Progesterone prepares the pregnancy’s uterine lining for implantation and keeps the normal pregnancy going.

The menstrual cycle is separated into two parts. The first phrase is follicular, and the second one is luteal.

The ovaries predominantly generate estrogen within the follicular phase. It is a hormone that drives follicular development and egg growth.

When estrogen hormone levels are enough, the pituitary gland releases luteinizing hormone (LH). It will encourage ovulation.

During the luteal stage, the egg gets fertile after ovulation. What remains of the follicle is known as the corpus luteum.

The main source of progesterone is secreted from the corpus luteum as a reaction to LH stimulation.

The increases in LH and progesterone production suggest a normal cycle with proper ovulation.

Estrogen and progesterone levels fall when a pregnancy cannot develop. It means the levels of HCG do not rise. It leads to the uterine lining cells dying, resulting in menstruation.

Why Do Doctors Give Progesterone To Some Women?

Pregnancy progesterone supplementation is advised for women with high chances of miscarriage.

These steroid hormones are for those who are experiencing vaginal bleeding and spotting. However, it might not help us avoid any inevitable miscarriage.

Who Can Progesterone Help?

When we are bleeding in the early phase, using progesterone may help us avoid miscarriage. It may work if you have had one or more miscarriages in the past.

When we use progesterone before becoming pregnant, it is ineffective.

It is also not an effective treatment when there is a positive pregnancy test but pregnancy cannot be detected on a scan. Plus, it is not advisable for women with ectopic pregnancy.

Our doctor will decide if it’s necessary to provide progesterone supplements. Based on our pregnancy history, they may consider this effective treatment.

They may urge us to avoid anal or vaginal intercourse, as well as any motions that may put a strain on our cervix.

Avoid strenuous exercise and household chores. We might continue with less physically demanding activities like yoga.

Can Progesterone Prevent Miscarriage?

It’s unfortunate that progesterone cannot prevent any miscarriage. It can be a traumatic experience.

However, It can assist women in achieving a healthy pregnancy following miscarriages.

Progesterone cannot help anticipated miscarriages in women with no previous miscarriages. Progesterone might be beneficial in situations with unexplained Recurrent Pregnancy Loss.

Given its safety, it is not unusual for many fertility doctors to provide this medicine. Sadly, the data is still ambiguous.

Numerous concerns remain unanswered, such as duration, preferred dose, and mode of administration.

Can Progesterone Stop Miscarriage?

In some cases, progesterone supplementation may be advised to help our pregnancy. Small clinical studies show that progesterone benefits women with a history of miscarriage.

Progesterone decreases the miscarriage rate by 5% when we have had one pregnancy loss. If we have had recurrent miscarriages, the success chances may increase by 15%.

The more miscarriages we had, the more effective progesterone was.

It works for women who have a condition called luteal phase defect. However, progesterone may not be effective in preventing miscarriage in all cases.

Miscarriage can occur for various reasons. It could be because of genetic abnormalities, infections, and other medical conditions.

Therefore, it is important to ask our doctor for a treatment plan.

Will I Miscarry If I Stop Taking Progesterone? 

Using progesterone throughout pregnancy is not an assurance against miscarriage. It is because several other variables might lead to pregnancy loss.

When the reason for miscarriage is not related to progesterone, we don’t need to do the treatment.

Even when the woman stops progesterone, she would not be at higher risk of miscarriage.

At roughly seven weeks, the placenta needs sufficient progesterone. Progesterone is commonly given to IVF patients or people after fertility treatment.

However, the optimal duration is still a question. Some research shows no risk when we stop progesterone in 5 weeks from about the time of a positive test at fresh embryo transfers.

The medicine could be offered until eight weeks of pregnancy in some cases. If a patient wants to stay longer, it is great. It should cause no harm, yet it is unnecessary.

Does Progesterone Delay Miscarriage?

Progesterone was discovered to delay the miscarriage diagnosis. It does not stop miscarriage. In other words, a pregnancy might cease to develop.

However, the progesterone doctors provide can conceal the miscarriage.

Just because studies haven’t proven that progesterone reduces loss does not suggest that no woman could benefit from it.

Giving progesterone to hundreds of women may be necessary to avoid one miscarriage.

The National Institute For Health And Care Excellence advises using it. Progesterone does not have any negative effects and is affordable.

How Long After Stopping Progesterone Will I Miscarry?

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There is a case of Ms. Courtney Jeannel, who shared her miscarriage story on the internet. She had a scan at 7 weeks and 5 days, and the hospital confirmed no fetal heartbeat.

She started miscarrying within 2 days after stopping the medicine. Her HCG took two months to get back to zero.

The time of miscarriage confirmation after stopping progesterone varied. It depends on each person’s condition.

As previously mentioned, the duration of progesterone supplementation cannot prevent any inevitable miscarriage.

It’s as though we’re gazing at a wrecked automobile. We can notice the dents in the body, but we might not see the internal damage.

When the engine is broken, repairing the outside cannot make it operate better.

The same is true for an embryo. Progesterone hormone cannot be used to repair an embryo.

How Does Progesterone Help With Fertility, Pregnancy, And Preventing Miscarriage?

Although progesterone cannot stop miscarriage, it does not mean we should not use it. Here are some benefits that progesterone can help pregnant women.

Preparing The Uterine Lining For Pregnancy?

High levels of progesterone support the uterine lining (endometrium) of the embryo. It will help the embryo to implant following fertilization in the luteal phase.

When our progesterone is normal, our endometrium will become thick and full of blood vessels.

It will be ready to take the implanted egg. These blood veins are critical as they take fertilized eggs. They feed the developing fetus and produce the placenta.

Maintaining Pregnancy

Throughout pregnancy, progesterone promotes uterine growth and prevents premature contractions.

It also improves the vascular system of the mother and helps the breasts for nursing.

Progesterone also helps the woman’s immune system against rejecting the genetically different fetus. 

The body usually perceives anything that is genetically different as a threat. However, progesterone prevents this from occurring in the fetus.

It is the reason why low progesterone may lead to miscarriage. Thus, progesterone therapy may be beneficial.

Preparing For Labor

Progesterone triggers cervix shortening. It will set up the uterus for contractions at full term. However, excessive progesterone could hinder labor.

Thus, progesterone medication is frequently discontinued after 36 weeks of pregnancy.

Balancing Estrogen Functions

Progesterone supplements counteract the negative impacts of estrogen. Estrogen usually increases the quantity of estrogen-sensitive cells, including endometrial cells.

Progesterone restricts the growth of endometrial cells. Meanwhile, it stimulates differentiation, which results in the formation of specialized cells.

Low progesterone activity leads to conditions characterized by excess estrogen activity.

When To Stop Progesterone In Pregnancy?

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Progesterone injections are frequently used from the start of pregnancy. It is usually from weeks of gestation (GW) 5-6 to GW 10-12 or GW 20.

It should be prescribed by our doctor when we feel cramps or bleeding.

Our doctor will decide whether or not to give progesterone. He or she will determine when to begin. Also, we should listen to our doctor about the continuation of progesterone supplementation. The decision will be based on the following factors:

  • Our previous pregnancies
  • If it was an IVF or natural pregnancy
  • Clinical results following uterine and cervical findings from ultrasound and physical exam.
  • Levels of liver enzymes 


How long after stopping progesterone will I miscarry? Actually, there is no clear answer. Some people would experience it after two days. However, it depends on our underlying reasons for miscarriage and health. It only takes two days for some people to have the signs of miscarriage.

One thing to note is that pregnancy might have stopped developing, and the progesterone just delays the diagnosis. However, we still need to follow our doctor’s instructions for the usage. It will benefit the future pregnancy.

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